Sickle cell disease and Bartonella spp. infection

Paulo Eduardo Neves Ferreira Velho, Marna Elise Ericson, David Mair, Kalpna Gupta
  • Paulo Eduardo Neves Ferreira Velho
    University of Campinas / University of Minnesota, United States |
  • Marna Elise Ericson
    University of Minnesota, USA,
  • David Mair
    American Red-Cross-North Central Region,
  • Kalpna Gupta
    University of Minnesota,


Sickle cell disease is the most common hereditary hematologic disorder in the world. Painful vaso-occlusive crises are the hallmark of the disease and it is difficult to treat. Chronic infection is related to a higher painful crisis rate in these patients. Bartonella spp. are fastidious bacteria of zoonotic transmission. They can cause human asymptomatic infection as well as fatal outcome. Pain, fatigue and fever, characteristic features of Bartonella spp. infection are manifest in sickle cell disease patients. Bartonella spp. infection should be ruled in sickle cell disease patients.


Bartonella; Sickle cell disease; Pain; Vaso-occlusive crises

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Submitted: 2014-06-13 09:34:20
Published: 2012-06-30 00:00:00
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