DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA

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Sabina Chiaretti
Gina Zini
Renato Bassan

Keywords

Acute Lymphoid Leukemia, ALL classification

Abstract

Acute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly in function of ALL subset, from standard chemotherapy in patients with standard-risk ALL, to allotransplantation (SCT) and targeted therapy in high-risk patients and cases expressing suitable biological targets, respectively. This review offers a glimpse on how best identify ALL and the most relevant ALL subsets. 

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Published
Oct 24, 2014
DOI https://doi.org/10.4084/mjhid.2014.073

Article Details

How to Cite

Chiaretti, S., Zini, G. and Bassan, R. (2014) “DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA”, Mediterranean Journal of Hematology and Infectious Diseases, 6(1), p. e2014073. doi: 10.4084/mjhid.2014.073.
Issue
Vol. 6 No. 1 (2014): Reviews, Articles, Case Reports and Letters
Section
Review Articles

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Transfer of Copyright and Permission to Reproduce Parts of Published Papers. Authors will grant copyright of their articles to the Institute of Hematology, Catholic University, Rome . No formal permission will be required to reproduce parts (tables or illustrations) of published papers, provided the source is quoted appropriately and reproduction has no commercial intent. Reproductions with commercial intent will require written permission and payment of royalties.

 

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