NASAL NK/T- CELL LYMPHOMA. COMPARATIVE ANALYSIS OF A MEXICAN POPULATION

Abstract

Nasal, natural-killer T-cell lymphoma (nasal NKTCL ), is a rare presentation of extranodal lymphoma in North-America and Europe, but in some countries, as China and Korea, it is extremely common: 20 to 46 % of  T-cell lymphomas. Some studies, analyzed the incidence in Latin-America, but Mexico,  based on political and geographic  considerations, was not  included in these reports. Thus, we performed a retrospective analysis of the patients diagnosed and treated  as nasal, NKTCL, in our institution, that is an academic tertiary national reference hospital. From 1988 to 2014, we diagnosed and treated  14,816 cases of non-Hodgkin’s  lymphoma,  10,957 (73%) were of B-cell  histology and 3822 (26%) were of T-cell histology. Nasal, NKTCL, was the most frequent  of  the T-cell histology: 40%. We compare our results with  other countries and  observed that  nasal, NKTCL  has a low  number of cases in North-America, and some countries in Latin-America, as Argentina, Brazil  and Chile,  but our  number will be similar to Guatemala and Peru, that were  similar to China and Korea.  We think that this neoplasm has a racial basis, independent  of environmental factors.