MJHID Educational Clinical Cases
Vol. 9 No. 1 (2017): Review, Original Articles, Case Reports
https://doi.org/10.4084/mjhid.2017.057

A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis

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Received: June 19, 2017
Accepted: September 17, 2017
Published: October 16, 2017
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Anemia, Neutropenia, , thrombocytopenia, hyperfeeeritinemia, Haemophagocytic lymphohistiocytosis

Authors

Monia Ouederni
moniahasan@yahoo.fr
Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia. Bone marrow transplantation center Tunis, Tunisia.
MONIA BEN KHALED
Faculty of Medicine, University of Tunis El Manar Bone marrow transplantation center Tunis, Tunisia.
Samia Rekaya
Faculty of Medicine, University of Tunis El Manar Bone marrow transplantation center Tunis, Tunisia.
Ilhem Ben Fraj
Faculty of Medicine, University of Tunis El Manar Bone marrow transplantation center Tunis, Tunisia.
Fethi Mellouli
Faculty of Medicine, University of Tunis El Manar Bone marrow transplantation center Tunis, Tunisia.
Mohamed Bejaoui
Faculty of Medicine, University of Tunis El Manar Bone marrow transplantation center Tunis, .
Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-boy presented with hepatosplenomegaly, severe anemia requiring repeated transfusions, thrombocytopenia, hypertriglyceridemia and very high hyperferritinemia. These clinical features of Hemophagocytic lymphohistiocytosis prompted a wide infectious and auto-immune request to be performed.  After a wide diagnostic workup, he was referred to the immune hematologic unit, for hemophagocytic lymphohistiocytosis  suspicion with unknown cause.

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How to Cite



“A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis” (2017) Mediterranean Journal of Hematology and Infectious Diseases, 9(1), p. e2017057. doi:10.4084/mjhid.2017.057.