Does splenectomy influence the development of Hypothyroidism in Transfusion Dependent Thalassemia Patients? A retrospective study. Splenectomy in Hypothyroidism of TDT patients

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Christos KATTAMIS
Prof

Myrto Skafida
Thalassemia Unit, Division Pediatric Hematology –Oncology, First Department of Pediatrics, National Kapodistrian University of Athens , “Aghia Sophia” Children Hospital, Athens, Greece.

Christalena Sofocleous
2Laboratory of Medical Genetics, National Kapodistrian University of Athens, Athens,Greece

Antonis Kattamis
Thalassemia Unit, Division Pediatric Hematology –Oncology, First Department of Pediatrics, National Kapodistrian University of Athens , “Aghia Sophia” Children Hospital, Athens, Greece.

Keywords

Transfusion Dependent Thalassemia; splenectomy; iron load grade; hypothyroidism; primary, central.

Abstract

To test the postulated hypothesis that splenectomy may influence the development of Hypothyroisdism (HT) in Transfused Dependent Thalassemia (TDT) young patients, basic factors known to influence the development of hypothyroidism were evaluated in 52 TDT adult patients (25 splenectomized) with HT. Precise analysis of data not only failed to disclose any statistical differences but revealed similarities, between splenectomized and non- splenectomized patients in respect to: i) the age at diagnosis of HT and ii)the ferritin levels on diagnosis and at the year of study. Interestingly a statistically higher age at diagnosis was recorded in central HT irrespective of splenectomy.

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Published
Oct 30, 2019
DOI https://doi.org/10.4084/mjhid.2019.064

Article Details

How to Cite

KATTAMIS, C. (2019) “Does splenectomy influence the development of Hypothyroidism in Transfusion Dependent Thalassemia Patients? A retrospective study.: Splenectomy in Hypothyroidism of TDT patients”, Mediterranean Journal of Hematology and Infectious Diseases, 11(1), p. e2019064. doi: 10.4084/mjhid.2019.064.
Issue
Vol. 11 No. 1 (2019): Review Articles, Original Articles, Scientific Letters, Case Reports, Letters to Editor.
Section
Scientific Letters

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