Vincenzo Accurso
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
https://orcid.org/0000-0003-4390-8388
Marco Santoro
Dept. of Surgical, Oncological and Stomatological Disciplines, University of Palermo
https://orcid.org/0000-0003-4390-8388
Salvatrice Mancuso
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
https://orcid.org/0000-0002-7926-090X
Angelo Davide Contrino
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
Paolo Casimio
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
Mariano Sardo
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
Simona Raso
Dept. of Surgical, Oncological and Stomatological Disciplines, University of Palermo
Florinda Di Piazza
Department of Surgical, Oncological and Stomatological Disciplines, Section of Medical Oncology, University of Palermo
Alessandro Perez
Department of Surgical, Oncological and Stomatological Disciplines, Section of Medical Oncology, University of Palermo
Marco Bono
Department of Surgical, Oncological and Stomatological Disciplines, Section of Medical Oncology, University of Palermo
Antonio Russo
Department of Surgical, Oncological and Stomatological Disciplines, Section of Medical Oncology, University of Palermo
Sergio Siragusa
Hematology Division University Hospital Policlinico "Paolo Giaccone" Palermo
Keywords
Essential Thrombocythemia, Polycythemia Vera
Abstract
Abstract
Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to determine the thrombotic event, including the interaction between platelets, leukocytes and endothelium alterations. Moreover, a very important role can be played by cardiovascular risk factors (CV.R) such as cigarette smoking habits, hypertension, diabetes, obesity and dyslipidemia. In this study we evaluated the impact that CV.R plays on thrombotic risk and survival in patients with PV and ET.