Giovanni D'Arena
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Roberto Guariglia
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Oreste Villani
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Maria Carmen Martorelli
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Giuseppe Pietrantuono
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Giovanna Mansueto
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Giuseppe Patitucci
Pathology Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Emilio Imbriani
Urology Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Tommaso Masciandaro
Urology Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Ludovica Borgia
Pathology Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Giulia Vita
Pathology Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Fiorella D'Auria
Laboratory of Clinical Research and Advanced Diagnostics, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Teodora Statuto
Laboratory of Clinical Research and Advanced Diagnostics, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
Pellegrino Musto
Hematology and Stem Cell Transplantation Unit,
IRCCS Centro di Riferimento Oncologico della Basilicata,
Rionero in Vulture (PZ), Italy
Keywords
chronic lymphocytic leukemia, prostate, penis, infiltration
Abstract
We report a patient with chronic lymphocytic leukemia (CLL) in whom a leukemic involvement of prostate and penis occurred in the advanced phase of his disease. Obstructive urinary symptoms were indicative of prostatic CLL infiltration, followed by the occurrence of an ulcerative lesion on the glans. Histologic examination confirmed the neoplastic B-cell infiltration. Both localizations responded to conventional treatments. A review of the literature confirms that leukemic involvement of the genito-urinary system is uncommon in CLL patients. However, such an involvement should be considered in CLL patients with urologic symptoms and a long history of the disease.
