Skin Manifestations associated with Mantle cell Lymphoma: a case report

Abstract

Mantle cell lymphoma (MCL) is a distinct type of non-Hodgkin’s lymphoma that commonly affects extra nodal sites. The most commonly affected sites are bone marrow, gastrointestinal tract and Waldeyer’s ring, however, skin is rarely involved. We report a case of 56 year-old gentleman with MCL; exhibiting multiple large maculopapular skin rashes and skin ulcers. Histopathological examination had not shown direct infiltration by any atypical cells. He had significant improvement of skin lesions with combination chemotherapy and debridement. Awareness of skin manifestations of MCL is essential for dermatologists and haematologists to establish the early diagnosis and timely administration of appropriate treatment.