About the Journal
The Mediterranean Journal of Hematology and Infectious Diseases was founded by Giuseppe Leone, Professor of Hematology at the Catholic University of Rome, in 2009, with the collaboration of Prof. Eligio Pizzigallo, Infectivologist, and Prof. Luigi Maria Larocca, Pathologist.
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The Journal publishes original articles and topical reviews concerning both clinical hematology and infectious diseases. A particular attention will be deserved to original article focusing on the relationship between blood and infectious diseases.
TRENDING
17:(1) (2025): 
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16:(1) (2024): ORIGINAL ARTICLES, REVIEWS:
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15:(1) (2023): ORIGINAL ARTICLES, REVIEWS:
14:(1) (2022): ORIGINAL ARTICLES, REVIEWS:
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13:(1) (2021): ORIGINAL ARTICLES, REVIEWS:
12:(1) (2020): ORIGINAL ARTICLES, REVIEWS:
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11:(1) (2019): ORIGINAL ARTICLES, REVIEWS:
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10:(1) (2018): ORIGINAL ARTICLES, REVIEWS:
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9:(1) (2017): ORIGINAL ARTICLES, REVIEWS:
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8:(1) (2016): ORIGINAL ARTICLES, REVIEWS:
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8:(Supplementary Issue) (2016): Fifth International Symposium on Secondary Leukemia and Leukemogenesis
7:(1) (2015): ORIGINAL ARTICLES, REVIEWS:
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6:(1) (2014): 
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5:(1) (2013): 
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4:(1) (2012): 
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3:(1) (2011): 
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ANNOUNCEMENTS
The Journal publishes original articles and topical reviews concerning both clinical hematology and infectious diseases. A particular attention will be deserved to original article focusing on the relationship between blood and infectious diseases.
TRENDING
17:(1) (2025): ORIGINAL ARTICLES, REVIEWS:
Reviews Topics:
16:(1) (2024): ORIGINAL ARTICLES, REVIEWS:
Reviews Topics:
15:(1) (2023): ORIGINAL ARTICLES, REVIEWS:
14:(1) (2022): ORIGINAL ARTICLES, REVIEWS:
Reviews Topics:
13:(1) (2021): ORIGINAL ARTICLES, REVIEWS:
12:(1) (2020): ORIGINAL ARTICLES, REVIEWS:
COVID-19 and Reviews Topics:
11:(1) (2019): ORIGINAL ARTICLES, REVIEWS:
Reviews Topics:
10:(1) (2018): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
9:(1) (2017): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
8:(1) (2016): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
8:(Supplementary Issue) (2016): Fifth International Symposium on Secondary Leukemia and Leukemogenesis
7:(1) (2015): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
6:(1) (2014): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
5:(1) (2013): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
4:(1) (2012): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
3:(1) (2011): ORIGINAL ARTICLES, REVIEWS:
Review Topics:
Announcements
This issue includes 4 review Articles, 4 Original Articles, 4 Scientific letters, and one Letter to the Editor.
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CURRENT ISSUE
Published: 2025-01-01
Vol. 17 No. 1 (2025): Review Articles, Original Article, Scientific Letter, Case Reports Letter to the Editor
Review Articles
FROM LEGACY TO INNOVATION: PIDOTIMOD’S EXPANDING THERAPEUTIC HORIZON
Abstract 1153 | PDF Downloads 656 HTML Downloads 201Page e2025057
WALDENSTRÖM MACROGLOBULINEMIA - A STATE-OF-THE-ART REVIEW: PART 2- FOCUS ON THERAPY
Abstract 1495 | PDF Downloads 1567 HTML Downloads 71Page e2025015
Guest Editor: Pellegrino Musto BISPECIFIC ANTIBODIES AND CAR T IN MULTIPLE MYELOMA: APPROPRIATE SELECTION OF PATIENTS AND SEQUENCING
Abstract 1115 | PDF Downloads 916 HTML Downloads 107Page e2025045
TOXICITIES ASSOCIATED WITH CAR-T CELL THERAPIES
Abstract 1213 | PDF Downloads 1002 HTML Downloads 80Page e2025039
Guest Edtor: Pellegrino Musto NOVELTIES ON MULTIPLE MYELOMA FROM THE MAIN 2024 HEMATOLOGY CONFERENCES
Abstract 1030 | PDF Downloads 1011 HTML Downloads 99Page e2025027
CUPROPTOSIS: A REVIEW ON MECHANISMS, ROLE IN SOLID AND HEMATOLOGICAL TUMORS, AND ASSOCIATION WITH VIRAL INFECTIONS
Abstract 814 | PDF Downloads 539 HTML Downloads 30Page e2025052
HEPARIN-BINDING PROTEIN AS A DIAGNOSTIC AND PROGNOSTIC MARKER OF INFECTIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Abstract 1259 | PDF Downloads 701 HTML Downloads 65 Suppl. Files Downloads 432Page e2025029
Guest Editor: Pellegrino Musto AN UPDATE OF THE APPROPRIATE SEQUENCING FOR SALVAGE THERAPIES IN MULTIPLE MYELOMA
Abstract 885 | PDF Downloads 754 HTML Downloads 87Page e2025043
PLASMA CELL LEUKEMIA UPDATE ON IMMUNOPHENOTYPE, MOLECULAR CHARACTERISTICS, AND THERAPY. The second part of plasma cell neoplasms with spreading in the blood and tissues
Abstract 256 | PDF Downloads 102 Html Downloads 13Page e2025080
Guest Editor: Pellegrino Musto HOW FIRST LINE THERAPY IS CHANGING IN TRANSPLANT-ELIGIBLE MULTIPLE MYELOMA PATIENTS
Abstract 1351 | PDF Downloads 1210 HTML Downloads 82Page e2025026
ATYPICAL DERMATOLOGICAL MANIFESTATIONS OF SYPHILIS IN ADVANCED HIV: A CASE-BASED NARRATIVE REVIEW
Abstract 946 | PDF Downloads 557 HTML Downloads 170Page e2025056
BRUTON’S TYROSINE KINASE (BTK) MUTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): A CLINICAL VIEW.
Abstract 849 | PDF Downloads 566 HTML Downloads 40Page e2025053
MANAGING INVASIVE FUNGAL INFECTIONS DURING ALLOGENEIC HEMATOPOIETIC TRANSPLANTATION: A 2025 UPDATE
Abstract 1178 | PDF Downloads 462 HTML Downloads 95Page e2025064
Guest Editor: Pellegrino Musto HOW FIRST-LINE THERAPY IS CHANGING IN NON-TRANSPLANT ELIGIBLE MULTIPLE MYELOMA PATIENTS.
Abstract 1114 | PDF Downloads 1053 HTML Downloads 77Page e2025025
OUTLINE OF IRON METABOLISM, WITH EMPHASIS TO ERYTHROID CELLS
Abstract 921 | PDF Downloads 430 Html Downloads 106Page e2025067
Guest Editor: Pellegrino Musto REFINING HIGH-RISK MULTIPLE MYELOMA: ADVANCEMENTS IN GENOMIC, CLINICAL, AND PROGNOSTIC CRITERIA
Abstract 1789 | PDF Downloads 1324 HTML Downloads 186Page e2025006
PLASMACELL NEOPLASMS WITH SPREADING IN THE BLOOD AND TISSUES: EXTRAMEDULLARY MYELOMA DISEASE A RARE AGGRESSIVE FORM OF MULTIPLE MYELOMA (First of two parts)
Abstract 1584 | HTML Downloads 195 PDF Downloads 710Page e2025005
Original Articles
The MINI-POLATUZUMAB VEDOTINE PLUS CHP (POLA-R-CHP) VS. MINI-R-CHOP IN PATIENTS OVER 80 YEARS OF AGE WITH DIFFUSE LARGE B-CELL LYMPHOMA: A RETROSPECTIVE, PROPENSITY SCORE-MATCHED ANALYSIS STRATIFIED BY SIMPLIFIED FRAILTY SCORE
Abstract 289 | PDF Downloads 127 HTML Downloads 17Page e2025070
T-CELL RECEPTOR (TCR)-VΒ REPERTOIRE FLOW CYTOMETRY FOR T-CELL LYMPHOPROLIFERATIVE DISORDER: A RETROSPECTIVE ANALYSIS OF A SINGLE-CENTER REAL-LIFE LABORATORY EXPERIENCE
Abstract 811 | PDF Downloads 739 Suppl. Files Downloads 572 HTML Downloads 75Page e2025016
PREDISPOSING FACTORS TO INFECTIONS IN THALASSEMIA SYNDROME PATIENTS
Abstract 897 | PDF Downloads 471 HTML Downloads 95Page e2025055
POST-LOAD PLASMA GLUCOSE INCREASE (PG-GAP) AS A RISK FACTOR FOR DEVELOPING DYSGLYCEMIA IN PATIENTS WITH TRANSFUSION-DEPENDENT Β-THALASSEMIA (Β-TDT): RETROSPECTIVE ANALYSIS OVER 8 YEARS
Abstract 219 | PDF Downloads 106 HTML Downloads 6Page e2025069
GREEK CONSENSUS ON CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) TREATMENT
Abstract 927 | HTML Downloads 76 PDF Downloads 735Page e2025014
VACCINATION FOLLOWING LEUKEMIA TREATMENT: VIRAL VACCINE RESPONSES IN SURVIVORS OF ACUTE LYMPHOBLASTIC LEUKEMIA
Abstract 522 | PDF Downloads 386 HTML Downloads 12Page e2025049
COMPARISON OF IL-34, ELASTOGRAPHY, AND BIOPSY IN THE ASSESSMENT OF LIVER FIBROSIS IN CHRONIC HEPATITIS B
Abstract 227 | PDF Downloads 120 Html Downloads 8Page e2025078
BASELINE THROMBIN GENERATION TEST DOES NOT PREDICT THROMBOTIC EVENTS IN ACUTE LEUKEMIA: A MONOCENTRIC PROSPECTIVE STUDY
Abstract 188 | PDF Downloads 80 Html Downloads 11Page e2025076
FASTING PLASMA GLUCOSE LEVELS WITHIN THE HIGH NORMAL RANGE ARE ASSOCIATED WITH A SIGNIFICANTLY INCREASED RISK OF FUTURE DYSGLYCEMIA IN TRANSFUSION-DEPENDENT Β THALASSEMIA: A DECADE-LONG MULTICENTER RETROSPECTIVE ANALYSIS
Abstract 215 | PDF Downloads 70 Html Downloads 9Page e2025072
MOLECULAR CHARACTERIZATION OF EPSTEIN - BARR VIRUS BASED ON EBNA3C PROTEIN AMONG HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS IN JORDAN
Abstract 630 | PDF Downloads 592 HTML Downloads 70Page e2025032
SEROLOGICAL AND MOLECULAR DETECTION OF RICKETTSIA SPP STEMMING FROM HEMATOPHAGOUS VECTORS IN PATIENTS WITH MENINGEAL SYNDROME IN NORTHERN ALGERIA
Abstract 472 | PDF Downloads 517 HTML Downloads 29Page e2025046
HEALTH-RELATED QUALITY OF LIFE MEASUREMENT IN ADULTS WITH SICKLE CELL DISEASE IN STEADY STATE: EXPERIENCE OF ONE FRENCH REFERENCE CENTER
Abstract 673 | PDF Downloads 333 Html Downloads 93Page e2025065
MOLECULAR MECHANISM OF TRAF6 IN MALIGNANT PROLIFERATION OF HUMAN NK/T CELL LYMPHOMA CELL HANK1
Abstract 170 | PDF Downloads 37 html Downloads 12Page e2025074
COULD PLASMA GLUCOSE (PG) INCREMENT (PG %) EXPAND THE CLINICAL WEIGHT OF OGTT? PRELIMINARY FINDINGS IN 19 TDT PATIENTS (Β-TDT) WITH NORMAL GLUCOSE TOLERANCE
Abstract 451 | PDF Downloads 346 HTML Downloads 18Page e2025050
PLASMODIUM VIVAX INFECTIONS IN DUFFY-NEGATIVE INDIVIDUALS: A PARADIGM SHIFT IN INDIAN MALARIA EPIDEMIOLOGY
Abstract 760 | PDF Downloads 627 HTML Downloads 46Page e2025044
ASSESSMENT OF THE EFFICACY OF PROCALCITONIN, C-REACTIVE PROTEIN AND ALBUMIN LEVELS-GUIDED ANTIBIOTICS USE IN SEPSIS
Abstract 689 | PDF Downloads 336 Html Downloads 88 Suppl. Files Downloads 122Page e2025060
EFFICACY OF VENETOCLAX COMBINED WITH AZACITIDINE IN ELDERLY PATIENTS WITH RELAPSED ACUTE MYELOID LEUKEMIA
Abstract 833 | PDF Downloads 433 Suppl. Files Downloads 266 Html Downloads 98Page e2025058
EVOLVING DISEASE SPECTRUM AND CHARACTERISTICS OF PEOPLE WITH HIV IN EASTERN CHINA: A 12-YEAR STUDY
Abstract 155 | PDF Downloads 64 Html Downloads 8Page e2025077
HEMATOPOIETIC STEM CELL TRANSPLANTATION IN SEVERE PEDIATRIC SICKLE CELL DISEASE: OUTCOME AND LONG-TERM COMPLICATIONS, SAUDI EXPERIENCE AT KING FAISAL SPECIALIST HOSPITAL, RIYADH, SAUDI ARABIA
Abstract 806 | PDF Downloads 719 HTML Downloads 247Page e2025030
ANALYSIS OF CLINICAL CHARACTERISTICS AND DIAGNOSTIC EFFICACY OF BLOOD INDICATORS IN NEONATAL SEPSIS WITH DIFFERENT PATHOGENIC BACTERIA
Abstract 471 | PDF Downloads 361 HTML Downloads 16Page e2025048
AN INEXPENSIVE CLINICAL-LABORATORY NOMOGRAM TO PREDICT POST-TREATMENT LUNG DESTRUCTION IN PULMONARY TUBERCULOSIS
Abstract 211 | PDF Downloads 75 Suppl. Files Downloads 17 Html Downloads 7Page e2025075
GROUP-BASED TRAJECTORY MODELING OF PLATELET IN PATIENTS WITH APLASTIC ANEMIA: A STUDY BASED ON THE MIMIC DATABASE
Abstract 741 | PDF Downloads 785 Suppl. Files Downloads 578 HTML Downloads 63Page e2025012
THE ROLE OF SLC22A4 IN ACUTE MYELOID LEUKEMIA
Abstract 180 | PDF Downloads 89 HTML Downloads 16Page e2025073
INTEGRATION OF CD200, CD43 AND ROR1 IN MULTIPARAMETER FLOW CYTOMETRY (MFC) ROUTINE PANELS FOR THE DIFFERENTIAL DIAGNOSIS OF B-CELL LYMPHOPROLIFERATIVE DISORDERS (B-LPDS)
Abstract 1717 | PDF Downloads 1234 HTML Downloads 215 PDF Downloads 918Page e2025.002
IMPACT OF RED CELL EXCHANGE TRANSFUSION ON INFLAMMATORY MARKERS IN SICKLE CELL DISEASE
Abstract 1484 | PDF Downloads 1179 HTML Downloads 173Page e2025011
CAUSAL RELATIONSHIP BETWEEN HELICOBACTER PYLORI ANTIBODIES AND IMMUNE THROMBOCYTOPENIA: A MENDELIAN RANDOMIZATION STUDY
Abstract 1302 | PDF Downloads 1079 PDF Downloads 851 HTML Downloads 178Page e2025.003
A MULTICENTER ICET-A SURVEY ON ADHERENCE TO ANNUAL ORAL GLUCOSE TOLERANCE TEST (OGTT) SCREENING IN TRANSFUSION-DEPENDENT THALASSEMIA (TDT) PATIENTS - THE EXPERT CLINICIANS’ OPINION ON FACTORS INFLUENCING THE ADHERENCE AND ON ALTERNATIVE STRATEGIES FOR ADHERENCE OPTIMIZATION
Abstract 2569 | PDF Downloads 1132 HTML Downloads 134Page e2025008
Scientific Letters
Bladder microbiota snapshots help to monitor urinary tract infections in vulnerable patients
Abstract 608 | PDF Downloads 544 HTML Downloads 76Page e2025028
Late-Onset Veno-Occlusive Disease (VOD) Post-Haploidentical Transplant: A Diagnostic Challenge Requiring Liver Biopsy– A Case Report
Abstract 675 | PDF Downloads 313 Html Downloads 87Page e2025068
Luspatercept Treatment in a β-Thalassemia Patient with Pulmonary Arterial Hypertension: A Case Report
Abstract 710 | PDF Downloads 362 Html Downloads 69Page e2025059
Prevention of Early Death in Very Elderly Acute Promyelocytic Leukemia Patients Using Lower Induction Doses of All-trans Retinoic Acid
Abstract 664 | PDF Downloads 448 Html Downloads 87Page e2025066
COVID-19 induces prolonged immunological exhaustion leading to relapse of hematological malignancies except in hematopoietic cell transplant recipients
Abstract 756 | PDF Downloads 567 HTML Downloads 71Page e2025042
Clinical spectrum and genotypes of children with alpha-thalassemia in northeastern, Thailand
Abstract 80 | PDF Downloads 41 Html Downloads 11Page e2025081
Zanubrutinib as upfront treatment in de-novo B-cell prolymphocytic leukemia: the case of two elderlies.
Abstract 781 | PDF Downloads 365 Html Downloads 78Page e2025061
Early use of thrombopoietin receptor agonists (Tpo-Ras) in clinical practice: results from an Italian survey on behalf of the GIMEMA Working Group Anemia and Thrombocytopenia
Abstract 672 | PDF Downloads 557 HTML Downloads 84Page e2025041
Elevated endogenous alveolar carbon monoxide concentration in patients with transfusion-dependent thalassemia and its relation to ineffective erythropoiesis
Abstract 417 | PDF Downloads 328 HTML Downloads 7Page e2025047
Long-term persistence of dysplastic features in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and arsenic trioxide
Abstract 738 | PDF Downloads 586 HTML Downloads 53Page e2025038
A case of multiple myeloma in a patient in treatment for chronic lymphocytic leukemia
Abstract 667 | PDF Downloads 587 HTML Downloads 84Page e2025033
Risk Factors of Hepatitis B Virus Infection in the Kurdistan Region of Iraq: A Cross-Sectional Study
Abstract 932 | PDF Downloads 742 HTML Downloads 92Page e2025018
Genetic modulators of diversity in biological expression of sickle cell anemia in patients from democratic republic of Congo
Abstract 1330 | HTML Downloads 171 PDF Downloads 976Page e2025001
Anti-mullerian hormone evaluates ovarian function in patients with non-transfusion-dependent thalassemia
Abstract 1097 | PDF Downloads 1025 HTML Downloads 119Page e2025007
The diagnostic sensitivity of beta-D-glucan assay in patients with chronic disseminated candidiasis
Abstract 1113 | PDF Downloads 959 PDF Downloads 805 HTML Downloads 103Page e2025009
Case Reports
Leukemia cutis in a patient with acute myeloid leukemia undergoing Azacitidine-Venetoclax: case presentation and review of the literature
Abstract 735 | PDF Downloads 856 HTML Downloads 48Page e2025013
Letters to the Editor
Addition of daratumumab to first-line therapy of newly diagnosed multiple myeloma in patients eligible for autologous stem cell transplantation: a single-center real-life experience
Abstract 751 | PDF Downloads 626 HTML Downloads 118Page e2025040
Thalidomide treatment for thrombocytopenia secondary to hypersplenism in children with β-thalassemia major: a case series
Abstract 658 | PDF Downloads 602 HTML Downloads 74Page e2025037
Genetically Predicted Antibody Levels as a Proxy for Helicobacter pylori Infection
Abstract 575 | PDF Downloads 657 HTML Downloads 37Page e2025021
Antimicrobial Stewardship in a world racked by conflict and uncertainty: A Call for global resilience
Abstract 117 | PDF Downloads 49 Html Downloads 11Page e2025071
Successful Management of Steroid-Resistant cutaneous Acute Graft-versus-Host Disease, Toxic Epidermal Necrolysis-Like, with Ruxolitinib
Abstract 704 | PDF Downloads 722 HTML Downloads 42Page e2025020
THE Co-Occurrence of Jak2/Calr-Positive Myeloproliferative Disorder and Bcr-Abl-Positive Chronic Myelogenous Leukaemia Treated with Combination of Tyrosine Kinase Inhibitors and Ruxolitinib.
Abstract 789 | PDF Downloads 785 HTML Downloads 66Page e2025023
A case of severe gastrointestinal toxicity after allogeneic hematopoietic stem cell transplantation: can we improve the evaluation of the “gut fitness“ ?
Abstract 461 | PDF Downloads 323 HTML Downloads 15Page e2025054
Monoclonal gammopathy of neurological significance: a case report and a novel approach
Abstract 702 | PDF Downloads 604 HTML Downloads 75Page e2025034
Direct oral anticoagulants (DOACs) in the onco-hematologic patients
Abstract 790 | PDF Downloads 813 HTML Downloads 43Page e2025022
Interstitial pneumonia triggered by H1N1 influenza A virus as the initial presentation of chronic myeloid leukemia
Abstract 689 | PDF Downloads 356 HTML Downloads 84 Suppl. Files Downloads 260Page e2025063
Clinical Manifestation of Children with Kawasaki Disease during the COVID-19 Pandemic in Iran: A Case Series
Abstract 617 | PDF Downloads 675 HTML Downloads 35Page e2025017
Efficacy and safety of teclistamab followed by autologous stem cells transplant in functional high-risk and triple class refractory multiple myeloma
Abstract 535 | PDF Downloads 441 HTML Downloads 13Page e2025051
Isavuconazole successfully treated pulmonary mucormycosis in acute myeloid leukemia: A case report
Abstract 626 | PDF Downloads 590 HTML Downloads 48Page e2025031
COVID-19-associated cold agglutinin syndrome and hemophagocytic phenomenon in a patient with monoclonal gammopathy of undetermined significance
Abstract 636 | PDF Downloads 688 HTML Downloads 44Page e2025024
CMV Reactivations During and after Letermovir Prophylaxis In Allogeneic Hematopoietic Stem Cell Transplantation: a Single-Center Experience.
Abstract 141 | PDF Downloads 65 Html Downloads 12Page e2025079
Fecal microbiota transplantation as a salvage therapy for concomitant resistant digestive graft versus host disease and cryptosporidiosis in a patient post hematopoietic stem cell transplant : about a case
Abstract 773 | PDF Downloads 633 HTML Downloads 45Page e2025035
Is laboratory monitoring useful in DOACs management?
Abstract 643 | PDF Downloads 693 HTML Downloads 50Page e2025019
Fusion Gene Landscape in a Case of Acute Myelocytic Leukemia with Myelocyte Morphology
Abstract 1023 | PDF Downloads 893 HTML Downloads 114Page e2025004
West Nile Virus Encephalitis in A Patient with Chronic Lymphocytic Leukemia
Abstract 1156 | PDF Downloads 964 HTML Downloads 103Page e2025010