Formulas for the Detection β-Thalassemia Carriers Are Affected by Changes in Red Cell Parameters

Deniz Aslan


Formulas, β-thalassemia carriers, red cell changes

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Submitted: 2018-02-09 09:42:55
Published: 2018-04-20 00:00:00
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-Roth IL, Lachover B, Koren G, Levin C, Zalman L, Koren A. Detection of β-Thalassemia Carriers by Red Cell Parameters Obtained from Automatic Counters using Mathematical Formulas. Mediterr J Hematol Infect Dis. 2018;10(1):e2018008.

-Clarke GM, Higgins TN. Laboratory investigation of hemoglobinopathies and thalassemias: review and update. Clin Chem. 2000;46:1284-1290.

-Maragoudaki E, Kanavakis E, Traeger-Synodinos J, Vrettou C, Tzetis M, Metaxotou-Mavrommati A, Kattamis C. Molecular, haematological and clinical studies of the -101 C --> T substitution of the beta-globin gene promoter in 25 beta-thalassaemia intermedia patients and 45 heterozygotes. Br J Haematol. 1999;107:699-706.

-Perseu L, Satta S, Moi P, Demartis FR, Manunza L, Sollaino MC, Barella S, Cao A, Galanello R. KLF1 gene mutations cause borderline HbA(2). Blood. 2011;118:4454-4458.

-Weatherall DJ. The Thalassemias. In: Beutler E, Coller BS, Lichtman MA, Kipps TJ, Seligsohn U., Eds. Williams Hematology. 6th Ed., New York: McGraw-Hill Company. 2001; 547-580.

-Aslan D, Altay C. Incidence of high erythrocyte count in infants and young children with iron deficiency anemia: re-evaluation of an old parameter. J Pediatr Hematol Oncol. 2003;25:303-306.

-Rund D, Oron-Karni V, Filon D, Goldfarb A, Rachmilewitz E, Oppenheim A. Genetic analysis of beta-thalassemia intermedia in Israel: diversity of mechanisms and unpredictability of phenotype. Am J Hematol. 1997;54:16-22.

-Velasco-Rodríguez D, Alonso-Domínguez JM, González-Fernández FA, Villarrubia J, Ropero P, Martínez-Nieto J, de la Fuente F, Guillén R, Acedo N, Serí C, Cava F. δβ-Thalassemia trait: how can we discriminate it from β-thalassemia trait and iron deficiency anemia? Am J Clin Pathol. 2014;142:567-573.

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