DISSEMINATED HISTOPLASMOSIS AS AIDS PRESENTATION. CASE REPORT AND COMPREHENSIVE REVIEW OF CURRENT LITERATURE

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Paola Zanotti
Claudia Chirico
Maurizio Gulletta
Laura Ardighieri
Salvatore Casari
Eugenia Quiros Roldan
Ilaria Izzo
Gabriele Pinsi
Giovanni Lorenzin
Fabio Facchetti
Francesco Castelli
Emanuele Focà *
(*) Corresponding Author:
Emanuele Focà | emanuelefoca@gmail.com

Abstract

Progressive disseminated histoplasmosis (PDH) is an AIDS-defining illness with a high lethality rate if not promptly treated. The wide range of its possible clinical manifestations represents the main barrier to diagnosis in non-endemic countries. Here we present a case of PDH with haemophagocytic syndrome in a newly diagnosed HIV patient and a comprehensive review of disseminated histoplasmosis focused on epidemiology, clinical features, diagnostic tools and treatment options in HIV-infected patients. 


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References

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