Daniele Ignazio La Milia1*, Sara Vincenti1*, Barbara Fiori2, Fabio Pattavina1, Riccardo Torelli1, Andrea Barbara2, Malgorzata Wachocka1 , Umberto Moscato2, Simona Sica2, Viviana Amato2, Walter Ricciardi2 and Patrizia Laurenti2.
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activities could cause dust contamination and fungal spores’
dissemination. A significant relationship was found between
building-work activities and the incidence of invasive aspergillosis,
in profoundly immunocompromised patients.
Materials and Methods
|Figure 1. Plan of Hematology ward under renovation activities. A) Building site 1 (BS1): the area marked by the black traced lines indicates the rooms undergoing restructuring (room1 and 2) and the phases in which environmental monitoring is carried out (T0 and T3 phases). The anteroom indicates the filter area accessible only to authorized personnel. The area outlined by the gray rectangle shows the rooms in which environmental monitoring is carried out during the initial and terminal phases of the construction site (T1 and T2 respectively). The area delimited with gray rectangle identifies the room in which environmental monitoring is carried out 1 week before the start of the works and which allows to define the Time of golden standard (TGS) value. B) Building site 2 (BS2) C) Building site 3 (BS3) and D) Building site 4 (BS4); the area marked by the black traced lines indicates the rooms undergoing restructuring (room1 and 2) and the phases in which environmental monitoring is carried out (T0 and T3 phases).|
|Figure 2. Bar graphs show the results of the airborne particle count (APC). Particle size is reported in the title of each graph. The phases at which the particle count is carried out are indicated in the legend: T0 before the beginning of the renovation activities (A-C-E-G), T1 and T2 initial and terminal phases of the renovation activities (A-C-E-G), and T3 after the sanification of the renovated rooms (B-D-F-H). Time of golden standard (TGS) represents the baseline value of particle count recorded 1 week before the start of renovation activities.|
|Figure 3. Total fungal counts were reported along the Y-axis from different building sites (BS1, BS2, BS3 and BS4). a) phases T0 (before the beginning of renovation activities), T1 at the beginning of activities and T2 at the end of activities and before the sanification procedures. The values of fungi total count for BS4 were b) phases T3 after the sanification of the renovated rooms. The presence of Aspergillus spp. was indicated by asterisk.|
|Table 1. Categorization of risk-groups for IA|