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western countries, about half of the hospitalized patients are anemic.
Generally, these patients are old, often with multiple diseases, and
anemia worsens the prognosis, finally increasing the risk of death. We
describe a monocentric observational study that evaluates 249
consecutive adult patients (160 women and 89 men) with anemia admitted
in the internal medicine department over five months. They represent
71.5% of all patients admitted in the study period. Demographic,
historical, and clinical data, laboratory tests, duration of
hospitalization, readmission at 30 days, and death were recorded.
Patients were stratified by age (75-84=old, >85 years=oldest-old),
anemia severity, and etiology of anemia.
Material and Methods
1. Main relevant data of anemic patients.
|Figure 1. Overall survival
after hospital admission was significantly worst in anemic than in not-
anemic patients (p=0.001). A significant reduction of survival
was found comparing old with and without anemia (p<0.001), but not
comparing anemic oldest old with non-anemic age matched even if a trend
can be appreciated.
|Table 2. Severity and causes of anemia.
|Figure 2. The prevalence of undetermined anemia is progressively reduced from mild to severe cases.
|Figure 3. Different causes
of anemia stratified on the basis of its severity. Figure 2A: old,
Figure 2B: oldest-old IDA= iron deficiency anemia, FIDA= functional
iron deficiency anemia.