Mario Schiavoni1, Carlo Pruneti2, Sara Guidotti2, Alessandra Moscatello3, Francesca Giordano4, Antonella Coluccia5, Rita Carlotta Santoro6, Maria Francesca Mansueto7, Ezio Zanon8, Renato Marino9, Isabella Cantori10 and Raimondo De Cristofaro11.
Director of Hemophilia and Rare Coagulopathies Center - Dept. of
Internal Medicine, "I. Veris Delli Ponti" Hospital-Scorrano-ASL Lecce,
2 Clinical Psychology, Clinical Psychophysiology, and Clinical Neuropsychology Labs., Dept. of Medicine and Surgery, University of Parma, Italy.
3 Penitentiary Medicine - Socio-sanitary District ASL-Lecce, Italy.
4 Service of Pathological Addictions-Gallipoli-ASL Lecce, Italy.
5 Hemophilia and Rare Coagulopathies Center -Dept. of Internal Medicine, " I. Veris Delli Ponti" Hospital-Scorrano-ASL Lecce, Italy.
6 Hemostasis and Thrombosis Unit, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
7 Regional Reference Center for Coagulopathies in Children and Adults, Hematology Unit, Oncology Dept.- Policlinico University, Palermo, Italy.
8 Multidisciplinary HUB Regional Center for Prevention, Prophylaxis, and Advanced Treatment of Hemophilic Arthropathy, General Medicine University Hospital of Padua, Italy.
9 Hemophilia and Thrombosis Center, Policlinico-University, Bari, Italy.
10 Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata, Macerata, Italy.
11 Hemorrhagic and Thrombotic Diseases Center, Foundation "A. Gemelli" IRCCS University Hospital, Rome, Italy.
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The health-related quality of life (HRQoL) of people with hemophilia
(PWH) is an important issue, especially considering people suffering
from chronic diseases beyond hemophilia. The principal aim of this
study was to investigate the presence and relevance of psychological
symptoms, both internalizing and externalizing, lifestyle, and HRQoL in
a group of Italian PWH with chronic bloodborne co-infections and
comorbidities. Furthermore, the research describes the association
between psychological aspects and the impact of disease-related
characteristics (type of hemophilia, presence of co-infections, and
comorbidities) on them.
Materials and Methods