Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature

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Riccardo Paggi
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Francesca Mariotti
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Jessica Mencarini
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Silvia Bresci
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Irene Capolmi
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Filippo Bartalesi
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Beatrice Borchi
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Luca Nassi
3 Hematology Unit, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

Alessandro Maria Vannucchi
4 Center for Innovation and Research in Myeloproliferative Neoplasms, Hematology Unit, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

Alessandro Bartoloni
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.

Keywords

Waldenström’s Macroglobulinemia, Invasive Aspergillosis, Orbital Lymphoma, Bruton Kinase Inhibitors, Lacrimal Glands Lymphoma×

Abstract

The use of specific inhibitory drugs of intracellular signaling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinemia (WM) is a recognized risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialties. 

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Published
Apr 28, 2023
DOI https://doi.org/10.4084/MJHID.2023.028

Article Details

How to Cite

Paggi, R. (2023) “Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature”, Mediterranean Journal of Hematology and Infectious Diseases, 15(1), p. e2023028. doi: 10.4084/MJHID.2023.028.
Issue
Vol. 15 No. 1 (2023): Review Articles, Original Article, Scientific Letter, Case Reports Letter to the Editor
Section
MJHID Educational Clinical Cases
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