@article{Intzes_Symeonidou_Zagoridis_Pentidou_Emmanouil_2021, title={SOCIOECONOMIC STATUS IS GLOBALLY A PROGNOSTIC FACTOR FOR OVERALL SURVIVAL OF MULTIPLE MYELOMA PATIENTS; SYNTHESIS OF STUDIES AND REVIEW OF THE LITERATURE: SES as prognostic factor for myeloma survival}, volume={13}, url={https://www.mjhid.org/mjhid/article/view/4369}, DOI={10.4084/mjhid.2021.006}, abstractNote={<p>Socioeconomic status (SES) is reflecting differences in sociodemographic factors affecting cancer survivorship. Deprived, low SES populations has a higher prevalence of multiple myeloma and worst survival, a gap that widens over time.</p> <p><strong>Methods</strong>: We performed a meta-analysis of 16 studies (registries and cohorts) reporting survival data of myeloma patients according to SES. Ten studies reported Hazzard Ratio (HR) (95 % CI) and 16 studies reported p values. We combined the HR from 10 studies and by using the Mosteller-Bush formula we performed the synthesis of p values according to the area of the globe.</p> <p><strong>Results: A combination</strong> of HR from 10 studies including 85198 myeloma patients weighted to sample size of each study and adopting the hypothesis of random effect returned a combined HR: 1,26 (1,13-1,31) in favor of high SES patients.</p> <p>USA: Synthesis of p values coming from  6 studies (n=89807 pts) by using the Mosteller and Bush formula extracted a p-value of <0.0001 favoring high SES patients</p> <p>Oceania: Synthesis of p values in two cohorts from Australia and New Zealand (n= 10196 pts) returned a p-value of 0,022 favoring high SES patients</p> <p>Europe: The synthesis of p values from UK and Greece studies (n=18533 pts) returned a p-value of <0,0001 favoring high SES patients</p> <p>Asia: Synthesis of 2 studies from Asia (n=915 pts) returned a p-value of <0,0001 favoring high SES patients</p> <p><strong>Conclusions:</strong> Across the globe and widening over decades socioeconomic status remains a gap for equality in myeloma care</p>}, number={1}, journal={Mediterranean Journal of Hematology and Infectious Diseases}, author={Intzes, Stergios and Symeonidou, Marianthi and Zagoridis, Konstantinos and Pentidou, Aikaterini and Emmanouil, Spanoudakis}, year={2021}, month={Jan.}, pages={e2021006} }