Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature

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Riccardo Paggi
Francesca Mariotti
Jessica Mencarini
Silvia Bresci
Irene Capolmi
Filippo Bartalesi
Beatrice Borchi
Luca Nassi
Alessandro Maria Vannucchi
Alessandro Bartoloni

Keywords

Waldenström’s Macroglobulinemia, Invasive Aspergillosis, Orbital Lymphoma, Bruton Kinase Inhibitors, Lacrimal Glands Lymphoma×

Abstract

The use of specific inhibitory drugs of intracellular signaling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinemia (WM) is a recognized risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialties. 

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